De Clercq, Erik: search on Z-Library

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1

Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection

Stittelaar, Koert J., Neyts, Johan, Naesens, Lieve, van Amerongen, Geert, van Lavieren, Rob F., Holý, Antonin, De Clercq, Erik, Niesters, Hubert G. M., Fries, Edwin, Maas, Chantal

Journal:

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

2

STRATEGIES IN THE DESIGN OF ANTIVIRAL DRUGS

De Clercq, Erik

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 4.45 MB

english, 2002

3

Suramin: A potent inhibitor of the reverse transcriptase of RNA tumor viruses

De Clercq, Erik

Journal:

Year:

1979

Language:

english

File:

PDF, 853 KB

english, 1979

4

Current and emerging non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV-1 treatment

Wang, Yali, De Clercq, Erik, Li, Guangdi

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2019

Language:

english

File:

PDF, 1.36 MB

english, 2019

5

Overview of Recent Strategic Advances in Medicinal Chemistry

Wu, Gaochan, Zhao, Tong, Kang, Dongwei, Zhang, Jian, Song, Yuning, Namasivayam, Vigneshwaran, Kongsted, Jacob, Pannecouque, Christophe, De Clercq, Erik, Poongavanam, Vasanthanathan, Liu, Xinyong, Zhan

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 3.78 MB

english, 2019

6

Relationship between the foot progression angle and eversion and exercise-related lower leg pain

Tine M Willems, Erik Witvrouw, Dirk De Clercq, Philip Roosen

Journal:

Journal of Foot and Ankle Research

Year:

2012

Language:

english

File:

PDF, 68 KB

english, 2012

7

Intrinsic gait-related risk factors for Achilles tendinopathy in novice runners: A prospective study

Ans Van Ginckel, Youri Thijs, Narmin Ghani Zadeh Hesar, Nele Mahieu, Dirk De Clercq, Philip Roosen, Erik Witvrouw

Journal:

Year:

2009

Language:

english

File:

PDF, 274 KB

english, 2009

8

Contralateral Risk Factors Associated with Exertional Medial Tibial Pain in Women

VERRELST, RUTH, DE CLERCQ, DIRK, WILLEMS, TINE MARIEKE, ROOSEN, PHILIP, WITROUW, ERIK

Journal:

Medicine & Science in Sports & Exercise

Year:

2014

Language:

english

File:

PDF, 2.87 MB

english, 2014

9

Suramin in the treatment of AIDS: Mechanism of action

Journal:

Antiviral Research

Year:

1987

Language:

english

File:

PDF, 499 KB

english, 1987

10

Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends

Zhan, Peng, Pannecouque, Christophe, De Clercq, Erik, Liu, Xinyong

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 3.58 MB

english, 2015

11

New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections

De Clercq, Erik

Journal:

Chemistry – An Asian Journal

Year:

2019

Language:

english

File:

PDF, 675 KB

english, 2019

12

Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF)

De Clercq, Erik

Journal:

Biochemical Pharmacology

Year:

2016

Language:

english

File:

PDF, 643 KB

english, 2016

13

Synthesis, In Vitro and In Vivo Release Kinetics, and Anti-HIV Activity of A Sustained-Release Prodrug (mPEG-AZT) of 3′-Azido-3′-deoxythymidine (AZT, Zidovudine)

Dr. Wenjun Li, Yu Chang, Peng Zhan, Prof. Dr. Na Zhang, Prof. Dr. Xinyong Liu, Prof. Dr. Christophe Pannecouque, Prof. Dr. Erik De Clercq

Journal:

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

14

Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives

Johan Neyts, Erik De Clercq

Journal:

Antiviral Research

Year:

2003

Language:

english

File:

PDF, 141 KB

english, 2003

15

A 40-Year Journey in Search of Selective Antiviral Chemotherapy*

De Clercq, Erik

Journal:

Annual Review of Pharmacology

Year:

2011

Language:

english

File:

PDF, 3.90 MB

english, 2011

16

Antiviral drugs: current state of the art

Journal:

Journal of Clinical Virology

Year:

2001

Language:

english

File:

PDF, 304 KB

english, 2001

17

Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs

Wang, Zhao, Yu, Zhao, Kang, Dongwei, Zhang, Jian, Tian, Ye, Daelemans, Dirk, De Clercq, Erik, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

18

Synthesis and biological activity of 4-thiazolidinones, thiosemicarbazides derived from diflunisal hydrazide

Güniz Küçükgüzel, Ayla Kocatepe, Erik De Clercq, Fikrettin Şahin, Medine Güllüce

Journal:

European Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 304 KB

english, 2006

19

Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones

Krishnan Suresh Kumar, Swastika Ganguly, Ravichandran Veerasamy, Erik De Clercq

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 170 KB

english, 2010

20

5-chloro-substituted derivatives of 2',3'-didehydro-2' ,3'-dideoxyuridine, 3'-fluoro-2' ,3'-dideoxyuridine and 3'-azido-2' ,3'-dideoxyuridine as anti-HIV agents

Jan Balzarini, Arthur Van Aerschot, Piet Herdewijn, Erik De Clercq

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 574 KB

english, 1989

21

Organic Chemist Whose Inventions Reshaped the Antiviral Drug World

De Clercq, Erik

Journal:

Medicinal Research Reviews

Year:

2013

Language:

english

File:

PDF, 446 KB

english, 2013

22

Historical Perspectives in the Development of Antiviral Agents Against Poxviruses

De Clercq, Erik

Journal:

Year:

2010

Language:

english

File:

PDF, 932 KB

english, 2010

23

Scapular Muscle Recruitment Pattern: Electromyographic Response of the Trapezius Muscle to Sudden Shoulder Movement Before and After a Fatiguing Exercise

Cools, Ann M., Witvrouw, Erik E., De Clercq, Geert A., Danneels, Lieven A., Willems, Tine M., Cambier, Dirk C., Voight, Michael L.

Journal:

Journal of Orthopaedic and Sports Physical Therapy

Year:

2002

Language:

english

File:

PDF, 75 KB

english, 2002

24

Approved Antiviral Drugs over the Past 50 Years

De Clercq, Erik, Li, Guangdi

Journal:

Clinical Microbiology Reviews

Year:

2016

Language:

english

File:

PDF, 9.36 MB

english, 2016

25

The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of l-ascorbic acid: Synthesis, cytostatic, and antiviral activity evaluations

Tatjana Gazivoda, Silvana Raić-Malić, Marko Marjanović, Marijeta Kralj, Krešimir Pavelić, Jan Balzarini, Erik De Clercq, Mladen Mintas

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 220 KB

english, 2007

26

An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice

Eyer, Ludek, Nougairède, Antoine, Uhlířová, Marie, Driouich, Jean-Sélim, Zouharová, Darina, Valdés, James J., Haviernik, Jan, Gould, Ernest A., De Clercq, Erik, de Lamballerie, Xavier, Ruzek, Daniel

Journal:

Journal of Virology

Year:

2019

Language:

english

File:

PDF, 3.60 MB

english, 2019

27

Differential inhibition of various deoxyribonucleic acid polymerases by Evans blue and aurintricarboxylic acid

Hideo NAKANE, Jan BALZARINI, Erik de CLERCQ, Katsuhiko ONO

Journal:

Year:

1988

Language:

english

File:

PDF, 561 KB

english, 1988

28

Synthesis and antiviral activity of monofluorinated cyclopropanoid nucleosides

Rosen, Thomas C., De Clercq, Erik, Balzarini, Jan, Haufe, G�nter

Journal:

Organic & Biomolecular Chemistry

Year:

2004

Language:

english

File:

PDF, 230 KB

english, 2004

29

1,2,3-Thiadiazole Thioacetanilides. Part 2 : Synthesis and Biological Evaluation of a New Series of 2-{[4-(3,4-Dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 Inhibitors

Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq

Journal:

Chemistry & Biodiversity

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

30

Antivirals and antiviral strategies

Clercq, Erik De

Journal:

Nature Reviews Microbiology

Year:

2004

Language:

english

File:

PDF, 544 KB

english, 2004

31

Correlation of Anti-HIV Activity with Anion Spacing in a Series of Cosalane Analogues with Extended Polycarboxylate Pharmacophores

Santhosh, Kalpathy C., Paul, Gitendra C., De Clercq, Erik, Pannecouque, Christophe, Witvrouw, Myriam, Loftus, Tracy L., Turpin, Jim A., Buckheit,, Robert W., Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 257 KB

english, 2001

32

Activity of the keggin polyoxotungstate pm-19 against herpes simplex virus type 2 infection in immunosuppressed mice: Role of peritoneal macrophage activation

Dr. Satoru Ikeda, Shigeki Nishiya, Akihiro Yamamoto, Toshihiro Yamase, Chiaki Nishimura, Erik De Clercq

Journal:

Journal of Medical Virology

Year:

1993

Language:

english

File:

PDF, 521 KB

english, 1993

33

Antiviral Activities of New Cidofovir Analogs Against Camelpox Virus, Used as a Model of Variola Virus, in Human Skin Equivalent Cultures

Sophie Duraffour, Robert Snoeck, Joost Van Den Oord, Marcela Krecmerová, Antonín Holý, Jean-Marc Crance, Daniel Garin, Erik De Clercq, Graciela Andrei

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 61 KB

english, 2007

34

Antiviral drugs in current clinical use

Journal:

Journal of Clinical Virology

Year:

2004

Language:

english

File:

PDF, 588 KB

english, 2004

35

Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents

İlkay Küçükgüzel, Esra Tatar, Ş. Güniz Küçükgüzel, Sevim Rollas, Erik De Clercq

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 394 KB

english, 2008

36

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

Lieve Naesens, Chad E. Stephens, Graciela Andrei, Arianna Loregian, Leen De Bolle, Robert Snoeck, J. Walter Sowell, Erik De Clercq

Journal:

Antiviral Research

Year:

2006

Language:

english

File:

PDF, 323 KB

english, 2006

37

Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs

Erik De Clercq, Richard T. Walker

Journal:

Pharmacology & Therapeutics

Year:

1984

Language:

english

File:

PDF, 2.80 MB

english, 1984

38

Current race in the development of DAAs (direct-acting antivirals) against HCV

De Clercq, Erik

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 472 KB

english, 2014

39

The discovery of novel diarylpyri(mi)dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2

Lu, Xueyi, Yang, Jiapei, Kang, Dongwei, Gao, Ping, Daelemans, Dirk, De Clercq, Erik, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

40

Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives

Deepika Sharma, Balasubramanian Narasimhan, Pradeep Kumar, Vikramjeet Judge, Rakesh Narang, Erik De Clercq, Jan Balzarini

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 225 KB

english, 2009

41

Antiviral activity of diverse classes of broad-acting agents and natural compounds in HHV-6-infected lymphoblasts

Lieve Naesens, Pascale Bonnafous, Henri Agut, Erik De Clercq

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 572 KB

english, 2006

42

HIV Inhibitors Targeted at the Reverse Transcriptase

DE CLERCQ, ERIK

Journal:

AIDS Research and Human Retroviruses

Year:

1992

Language:

english

File:

PDF, 1.99 MB

english, 1992

43

5-Hydroxypyrido[2,3- b ]pyrazin-6(5 H )-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase

Sun, Lin, Gao, Ping, Dong, Guanyu, Zhang, Xujie, Cheng, Xiqiang, Ding, Xiao, Wang, Xueshun, Daelemans, Dirk, De Clercq, Erik, Pannecouque, Christophe, Menéndez-Arias, Luis, Zhan, Peng, Liu, Xinyong

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 796 KB

english, 2018

44

In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil

Pieter Annaert, Josef J. Tukker, Jan van Gelder, Lieve Naesens, Erik de Clercq, Guy van den Mooter, Renaat Kinget, Patrick Augustijns

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

45

Synthesis and Antileishmanial Activity of (1,3-Benzothiazol-2-yl) Amino-9-(10H)-acridinone Derivatives.

Florence Delmas, Antonio Avellaneda, Carole Di Giorgio, Maxime Robin, Erik De Clercq, Pierre Timon-David, Jean-Pierre Galy

Journal:

Year:

2004

File:

PDF, 15 KB

2004

46

Antivirals: Past, present and future

De Clercq, Erik

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 383 KB

english, 2013

47

Design, Synthesis, Anti-HIV Activities, and Metabolic Stabilities of Alkenyldiarylmethane (ADAM) Non-nucleoside Reverse Transcriptase Inhibitors

Silvestri, Maximilian A., Nagarajan, Muthukaman, De Clercq, Erik, Pannecouque, Christophe, Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 312 KB

english, 2004

48

Synthesis and antiviral activity of 2-deoxy-1,5-anhydro-D-mannitol nucleosides containing a pyrimidine base moiety

María-Jesús Pérez-Pérez, Erik De Clercq, Piet Herdewijn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 210 KB

english, 1996

49

Three decades of antiviral drugs

Clercq, Erik De

Journal:

Nature Reviews Drug Discovery

Year:

2007

Language:

english

File:

PDF, 107 KB

english, 2007

50

Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.

Saboulard, Didier, Naesens, Lieve, Cahard, Dominique, Salgado, Antonio, Pathirana, Ranjith, Velazquez, Sonsoles, McGuigan, Christopher, {De Clercq}, Erik, Balzarini, Jan

Journal:

Molecular Pharmacology

Year:

1999

Language:

english

File:

PDF, 212 KB

english, 1999

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